Utente:Grasso Luigi/sanbox1/1,2-DCP
| 1,2-dicloropropano | |
|---|---|
 | |
| Nome IUPAC | |
| [1][2] | |
| Caratteristiche generali | |
| Massa molecolare (u) | [3] |
| Numero CAS | |
| Proprietà chimico-fisiche | |
| Solubilità in acqua | 0.4% (20°C)[4] |
| Tensione di vapore (Pa) a 295 K | 19 mmHg (20°C)[4] |
| Dati farmacologici | |
| Categoria farmacoterapeutica | antibiotici, tetracicline |
| Modalità di somministrazione | orale |
| Indicazioni di sicurezza | |
| Simboli di rischio chimico | |
 
| |
| attenzione | |
| Frasi H | --- |
| Consigli P | ---[5]---[6] |
1,2-Dichloropropane is an organic compound classified as a chlorocarbon. It is a colorless, flammable liquid with a sweet odor. it is obtained as a byproduct of the production of epichlorohydrin, which is produced on a large scale.[7]
Applicazioni[modifica | modifica wikitesto]
1,2-Dichloropropane is an intermediate in the production of perchloroethylene and other chlorinated chemicals.[7] It was once used as a soil fumigant, chemical intermediate,kort2137 as well as an industrial solvent and was found in paint strippers, varnishes, and furniture finish removers but some of these uses have been discontinued.[8]
Carcinogenity[modifica | modifica wikitesto]
Following several cases of bile duct cancer among Japanese printing firm employees, an investigation by the Japanese Ministry of Health, Labour and Welfare concluded in March 2013 that these cases were likely due to the use of cleaning agents containing 1,2-dichloropropane. Thus, there is reasonable evidence that 1,2-dichloropropane may be a carcinogen.[9][10]
Data from animal studies show tumor growth in the liver and mammary glands.[11] Further animal studies involving inhalation toxicity data has caused the National Institute for Occupational Safety and Health to classify 1,2-dichloropropane as a carcinogen and IDLH.[12]
Dicloropropani[modifica | modifica wikitesto]
Abbiamo i seguenti isomeri di posizione (4) del propano disostituito da atomi di solo cloro C3H6Cl2.
| Formula struttura | Nomenclatura |
|---|---|
| C2H5CHCl2 | 1,1-dicloropropano |
| CH2ClCHClCH3 | 1,2-dicloropropano |
| CH2ClCH2CH2Cl | 1,3-dicloropropano |
| CH3CCl2CH3 | 2,2-dicloropropano |
Note[modifica | modifica wikitesto]
- ^ (EN) PubChem Compound, AC1L1C0X - Compound Summary, su pubchem.ncbi.nlm.nih.gov, National Center for Biotechnology Information, 25 Marzo 2005. URL consultato il 13 Ottobre 2011.
- ^ (EN) Chemical Entities of Biological Interest, methanediyl (CHEBI:29357), su ebi.ac.uk, EBI (UK), 14-01-2009. URL consultato il 02-01-2012.
- ^ (EN) IUPAC Commission on Isotopic Abundances and Atomic Weights., Atomic weights of the elements 2017, su Queen Mary University of London.
- ^ a b (EN) NIOSH Pocket Guide to Chemical Hazards, 1,1,2-Trichloroethane, su cdc.gov, NIOSH.
- ^ Scheda del composto su IFA-GESTIS
- ^ Scheda del composto su ARPA
- ^ a b Manfred Rossberg, Wilhelm Lendle, Gerhard Pfleiderer, Adolf Tögel, Eberhard-Ludwig Dreher, Ernst Langer, Heinz Rassaerts, Peter Kleinschmidt, Heinz Strack, Richard Cook, Uwe Beck, Karl-August Lipper, Theodore R. Torkelson, Eckhard Löser, Klaus K. Beutel, Trevor Mann "Chlorinated Hydrocarbons" in Ullmann's Encyclopedia of Industrial Chemistry 2006, Wiley-VCH, Weinheim. DOI: 10.1002/14356007.a06_233.pub2.
- ^ ToxFAQs for 1,2-Dichloropropane, su atsdr.cdc.gov.
- ^ Report by the Japanese Ministry of Health, Labour and Welfare
- ^ Article in the Yomiuri Shinbun
- ^ CDC - NIOSH Pocket Guide to Chemical Hazards
- ^ Documentation for Immediately Dangerous To Life or Health Concentrations (IDLHs)
