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== Bibliografia == |
== Bibliografia == |
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* {{cite book|author=Marc Diederich|title=Natural Compounds and Their Role in Apoptotic Cell Signaling Pathways|url=http://books.google.com/books?id=NXDACGRU0U0C&pg=PA202|accessdate= |year=2009|publisher=John Wiley and Sons|isbn=978-1-57331-737-5|pages=202–}} |
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* {{cite book|author1=Friedrich Marks|author2=Gerhard F?rstenberger|title=Prostaglandins, Leukotrienes, and Other Eicosanoids: From Biogenesis to Clinical Applications|url=http://books.google.com/books?id=uc7N2Ur6bpMC&pg=PA324|accessdate= |date=9 December 2008|publisher=John Wiley & Sons|isbn=978-3-527-61363-2|pages=324–}} |
* {{cite book|author1=Friedrich Marks|author2=Gerhard F?rstenberger|title=Prostaglandins, Leukotrienes, and Other Eicosanoids: From Biogenesis to Clinical Applications|url=http://books.google.com/books?id=uc7N2Ur6bpMC&pg=PA324|accessdate= |date=9 December 2008|publisher=John Wiley & Sons|isbn=978-3-527-61363-2|pages=324–}} |
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* {{cite book|author=Rudi Beyaert|title=Nuclear factor kB: regulation and role in disease|url=http://books.google.com/books?id=74oFx9zZ2X0C&pg=PA213|accessdate=27 December 2011|year=2003|publisher=Springer|isbn=978-1-4020-1434-5|pages=213–}} |
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* {{cite book|author=A. Gilbert|title=Photochemistry|url=http://books.google.com/books?id=tyZ2luyatE8C&pg=PA75|accessdate= |date=31 October 2001|publisher=Royal Society of Chemistry|isbn=978-0-85404-430-6|pages=75–}} |
* {{cite book|author=A. Gilbert|title=Photochemistry|url=http://books.google.com/books?id=tyZ2luyatE8C&pg=PA75|accessdate= |date=31 October 2001|publisher=Royal Society of Chemistry|isbn=978-0-85404-430-6|pages=75–}} |
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* {{cite book|author1=Alfred Hassner|author2=Irishi Namboothiri|title=Organic Syntheses Based on Name Reactions: A Practical Guide to 750 Transformations|url=http://books.google.com/books?id=YqxIdquArl0C&pg=PA335|accessdate |
* {{cite book|author1=Alfred Hassner|author2=Irishi Namboothiri|title=Organic Syntheses Based on Name Reactions: A Practical Guide to 750 Transformations|url=http://books.google.com/books?id=YqxIdquArl0C&pg=PA335|accessdate |date= |publisher=Elsevier|isbn=978-0-08-096630-4|pages=335–}} |
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* {{cite book|author=Corey R. Woods|title=Trends in DNA research|url=http://books.google.com/books?id=vxBh8EQTupcC&pg=PA1|accessdate= |date=3 June 2006|publisher=Nova Publishers|isbn=978-1-59454-635-8|pages=1–}} |
* {{cite book|author=Corey R. Woods|title=Trends in DNA research|url=http://books.google.com/books?id=vxBh8EQTupcC&pg=PA1|accessdate= |date=3 June 2006|publisher=Nova Publishers|isbn=978-1-59454-635-8|pages=1–}} |
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* {{cite book|author1=Angelo Albini|author2=Maurizio Fagnoni|title=Handbook of synthetic photochemistry|url=http://books.google.com/books?id=X3EzUeXrSdEC&pg=PA175|accessdate= |date=16 March 2010|publisher=John Wiley & Sons|isbn=978-3-527-32391-3|pages=175–}} |
* {{cite book|author1=Angelo Albini|author2=Maurizio Fagnoni|title=Handbook of synthetic photochemistry|url=http://books.google.com/books?id=X3EzUeXrSdEC&pg=PA175|accessdate= |date=16 March 2010|publisher=John Wiley & Sons|isbn=978-3-527-32391-3|pages=175–}} |
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*{{cite book|author=Channing J. Der|title=RAS family GTPases|url=http://books.google.com/books?id=Ht1bypUY7c8C&pg=PA32|accessdate= |date=19 October 2006|publisher=Springer|isbn=978-1-4020-4328-4|pages=32–}} |
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{{Portale|medicina}} |
{{Portale|medicina}} |
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Versione delle 17:36, 27 dic 2011
La Prostaglandina Ciclopentenone (cyPG) è un tipo di prostaglandina che regola l'infiammazione e altri processi. Si tratta di un nuovo potenziale bersaglio per attività di tipo anti-infiammatorie. Si ritiene che esso agisca come antinfiammatorio inibendo l'attivazione di NF-kB, un fattore di trascrizione nella riproduzione delle cellule.
La prostaglandina ciclopentenone conosciuta come D15-PGJ2 ha dimostrato di inibire un gene attivatore delle cellule T attivo nel processo infiammatorio, come in diverse malattie autoimmuni.[1][2]
Note
- ^ Fionda C, Nappi F, Piccoli M, Frati L, Santoni A, Cippitelli M, Inhibition of trail gene expression by cyclopentenonic prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in T lymphocytes, in Mol. Pharmacol., vol. 72, n. 5, November 2007, pp. 1246–57, DOI:10.1124/mol.107.038042, PMID 17673570.
- ^ Cernuda-Morollón E, Pineda-Molina E, Cañada FJ, Pérez-Sala D, 15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit, in J. Biol. Chem., vol. 276, n. 38, September 2001, pp. 35530–6, DOI:10.1074/jbc.M104518200, PMID 11466314.
Bibliografia
- Marc Diederich, Natural Compounds and Their Role in Apoptotic Cell Signaling Pathways, John Wiley and Sons, 2009, pp. 202–, ISBN 978-1-57331-737-5.
- Prostaglandins, Leukotrienes, and Other Eicosanoids: From Biogenesis to Clinical Applications, John Wiley & Sons, 9 December 2008, pp. 324–, ISBN 978-3-527-61363-2.
- Rudi Beyaert, Nuclear factor kB: regulation and role in disease, Springer, 2003, pp. 213–, ISBN 978-1-4020-1434-5. URL consultato il 27 December 2011.
- A. Gilbert, Photochemistry, Royal Society of Chemistry, 31 October 2001, pp. 75–, ISBN 978-0-85404-430-6.
- Organic Syntheses Based on Name Reactions: A Practical Guide to 750 Transformations, Elsevier, pp. 335–, ISBN 978-0-08-096630-4.
- Corey R. Woods, Trends in DNA research, Nova Publishers, 3 June 2006, pp. 1–, ISBN 978-1-59454-635-8.
- Handbook of synthetic photochemistry, John Wiley & Sons, 16 March 2010, pp. 175–, ISBN 978-3-527-32391-3.
- Channing J. Der, RAS family GTPases, Springer, 19 October 2006, pp. 32–, ISBN 978-1-4020-4328-4.