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Template:Infobox diagnostic

Il tasso alcolemico, chiamato anche tasso alcolico, è una grandezza spessa utilizzata per quantificare un'intossicazione alcolica per fini medici o legali.

Il tasso alcolemico è generalmente espresso come concentrazione di etanolo nel sangue in unità di massa di alcol su volume del sangue o massa di alcol su massa del sangue, a seconda della normativa di referimento. Per esempio, in Italia un tasso alcolemico di 0,1 indica che sono presenti 0,1 g di alcol per ogni litro di sangue.

Effetti del tasso alcolemico

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Lo stesso argomento in dettaglio: Effetti a breve termine del consumo di alcol.
Progressive effects of alcohol[1]
Tasso alcolemico (g/L) Comportamento Indebolimento
0,01–0,29
  • Comportamento normale
  • Tenui effetti che possono essere rilevati tramite speciali test
0,30–0,59
  • Euphoria lieve
  • Rilassamento
  • Gioia
  • Loquacità
  • Minore inibizione
  • Concentrazione
0,60–0,99
  • Emozioni smorzate
  • Minore sensibilità al dolore
  • Euforia
  • Disinibizione
  • Estroversione
  • Ragionamenti
  • Percezione della profondità
  • Visione periferica
  • Riflesso pupillare
1,00–1,99
  • Comportamento esagerato
  • Iperattività
  • Possibili nausea e vomito
  • Riflessi
  • Tempo di reazione
  • Controllo delle abilità motorie
  • Barcollare
  • Farfugliare
  • Temporanea disfunzione erettile
2,00–,2,99
  • Nausea
  • Vomito
  • Sbalzi emozionali
  • Angressività o tristezza
  • Parziale incapacità di comprensione
  • Sensazioni alterate
  • Libido diminuito
  • Possibile stupor
3,00–3,99
4,00–5,00
  • Grave depressione del sistema nervoso centrale
  • Coma
  • Rischio di morte
  • Respirazione
  • Frequenza Cardiaca
  • Nistagmo alcolico
>5,00
  • Alto rischio di morte

Stima del tasso alcolemico a seconda del consumo

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Template:Further information Per stimare il picco del tasso alcolemico, è usata una variazione della formula di Widmark che include il lasso di tempo in cui si è bevuto. La formula è[2]

dove :

  • 0.806 è una costante equivalente alla concetrazione di acqua nel sangue (ovvero 80.6%),
  • SD è il numero di standard drink, equivalente a 10 g di etanolo,
  • 1.2 è un fattore per convertire i grammi in standard Svedesi, stabilito dall'Istituto Nazionale Svedese della Sanità Pubblica,
  • BW è la constante di acqua corporea (0,58 per gli uomini e 0,49 per le donne),
  • Wt è il peso corporeo (in kilogrammi),
  • MR è la costante del metabolismo (0.017) e
  • DP è il lasso di tempo in cui si è bevuto in ore.[2]

Riguardo il metaabolismo (MR); individui di sesso femminile mostrano un tasso medio di eliminazione più alto (mediamente 0,017; compreso tra 0,014-0,021 g/210 L) rispetto ai maschi (in media 0,015; compreso tra 0,013-0,017 g/210 L). I soggetti femminili hanno mediamente una maggiore percentuale di grasso nel corpo (26,0; compresa tra 16,7-36,8%) rispetto ai maschi (18,0; compreso tra 10,2-25,3%).[3] Inoltre, gli uomini sono mediamente pi\ pesanti delle donne ma non è accurato dire che solo il contenuto di acqua nel corpo è responsabile per l'eliminazione dell'alcol dal corpo, perché l'alcol si dissolve anche nei tessuti adiposi. Quando cià accade, una certa quantità di alcol è temporaneamente tolta dal sangue e immagazzinata nel grasso. Per questo motivo, buona parte delle stime della qauntità di alcol nel corpo usano semplicemente il peso dell'individuo, e non il suo contenuto di acqua. Infine, è stato supposto che le bollicine in vini frizzanti possano velocizzare l'intossicazione alcolica aiutando l'alcol a raggiungere il sangue più velocemente. In uno studio condotto all'Università del Surrey, Gran Bretagna, sono state somministrate a varie persone uguali quantità di Champagne frizzante e non, che contenevano la stessa quanità di alcol. Dopo 5 minuti dopo la consumazione, il gruppo a cui era stato somministrato il vino frizzante aveva 54 mg di alcol nel sangue mentre il gruppo ceh aveva bevuto lo stesso vino, non frizzante, aveva assunto 39 gs.[4]

Examples:

  • 80 kg male drinking 3 standard drinks in two hours:
  • 70 kg woman drinking 2.5 standard drinks in two hours:
Standard drink chart (U.S.)[5]
Alcohol Amount (ml) Amount (fl oz) Serving size Alcohol (% by vol.) Alcohol
80 proof liquor 44 1.5 One shot 40 0,6 US fl oz (18 ml)
Table wine 148 5 One glass 12 0,6 US fl oz (18 ml)
Beer 355 12 One can/bottle 5 0,6 US fl oz (18 ml)

Note: This chart defines a drink as 14g of ethanol, while the formula defines a drink as 10g of ethanol.

Male
Female
Approximate blood alcohol percentage (by vol.)[6]
One drink has 0,5 US fl oz (15 ml) alcohol by volume
Drinks Body weight
40 kg 45 kg 55 kg 64 kg 73 kg 82 kg 91 kg 100 kg 109 kg
90 lb 100 lb 120 lb 140 lb 160 lb 180 lb 200 lb 220 lb 240 lb
1
0.05
0.04
0.05
0.03
0.04
0.03
0.03
0.02
0.03
0.02
0.03
0.02
0.02
0.02
0.02
0.02
0.02
2
0.10
0.08
0.09
0.06
0.08
0.05
0.07
0.05
0.06
0.04
0.05
0.04
0.05
0.03
0.04
0.03
0.04
3
0.15
0.11
0.14
0.09
0.11
0.08
0.10
0.07
0.09
0.06
0.08
0.06
0.07
0.05
0.06
0.05
0.06
4
0.20
0.15
0.18
0.12
0.15
0.11
0.13
0.09
0.11
0.08
0.10
0.08
0.09
0.07
0.08
0.06
0.08
5
0.25
0.19
0.23
0.16
0.19
0.13
0.16
0.12
0.14
0.11
0.13
0.09
0.11
0.09
0.10
0.08
0.09
6
0.30
0.23
0.27
0.19
0.23
0.16
0.19
0.14
0.17
0.13
0.15
0.11
0.14
0.10
0.12
0.09
0.11
7
0.35
0.26
0.32
0.22
0.27
0.19
0.23
0.16
0.20
0.15
0.18
0.13
0.16
0.12
0.14
0.11
0.13
8
0.40
0.30
0.36
0.25
0.30
0.21
0.26
0.19
0.23
0.17
0.20
0.15
0.18
0.14
0.17
0.13
0.15
9
0.45
0.34
0.41
0.28
0.34
0.24
0.29
0.21
0.26
0.19
0.23
0.17
0.20
0.15
0.19
0.14
0.17
10
0.51
0.38
0.45
0.31
0.38
0.27
0.32
0.23
0.28
0.21
0.25
0.19
0.23
0.17
0.21
0.16
0.19
Subtract approximately 0.01 every 40 minutes after drinking.

Binge drinking

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Lo stesso argomento in dettaglio: Binge drinking.

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) define the term "binge drinking" as a pattern of drinking that brings a person’s blood alcohol concentration (BAC) to 0.08 grams percent or above. This typically happens when men consume 5 or more drinks, and when women consume 4 or more drinks, in about 2 hours.[7]

Units of measurement

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There are several different units in use around the world for defining blood alcohol concentration. Each is defined as either a mass of alcohol per volume of blood or a mass of alcohol per mass of blood (never a volume per volume). 1 milliliter of blood has a mass of approximately 1.06 grams. Because of this, units by volume are similar but not identical to units by mass. In the U.S. the concentration unit 1% w/v (percent mass/volume, equivalent to 10 g/l or 1 g per 100 ml) is in use.[8] This is not to be confused with the amount of alcohol measured on the breath, as with a breathalyzer. The amount of alcohol measured on the breath is generally accepted as proportional to the amount of alcohol present in the blood at a rate of 1:2100. Therefore, a breathalyzer measurement of 0.10 mg/L of breath alcohol converts to 0.0001×2100 g/10dL, or 0.021 g/dL of blood alcohol (the units of the BAC in the United States). While a variety of units (or sometimes lack thereof) is used throughout the world, many countries use the g/L unit, which does not create confusion as percentages do. Usual units are highlighted in the table below.

Reference Unit Dimensions Equivalent to Used in
BAC by volume 1 percent (%) 1/100 g/mL = 1 g/dL 9.43 mg/g, 217.4 mmol/L United States, Australia, Canada
1 permille (‰) 1/1000 g/mL = 1 g/L 0.943 mg/g, 21.7 mmol/L Austria, Belgium, Bulgaria, France, Latvia, Lithuania, Netherlands, Poland, Romania, Spain, Switzerland, Turkey
1 basis point (‱) 1/10,000 g/mL = 10 mg/100 mL 94.3 ppm, 2.17 mmol/L United Kingdom
BAC by mass 1 percent (%) 1/100 g/g = 1 cg/g 1.06 cg/mL, 230 mmol/L
1 permille (‰) 1/1000 g/g = 1 mg/g 1.06 mg/mL, 23 mmol/L Finland, Norway, Sweden, Denmark, Germany, Ireland, Russian Federation
1 part per million (ppm) 1/1,000,000 g/g = 1 μg/g 1.06 μg/mL, 23 μmol/L

Template:Further information

Map of Europe showing countries' blood alcohol limits as defined in g/dl for the general population.

For purposes of law enforcement, blood alcohol content is used to define intoxication and provides a rough measure of impairment. Although the degree of impairment may vary among individuals with the same blood alcohol content, it can be measured objectively and is therefore legally useful and difficult to contest in court. Most countries disallow operation of motor vehicles and heavy machinery above prescribed levels of blood alcohol content. Operation of boats and aircraft are also regulated.

The alcohol level at which a person is considered legally impaired varies by country. The list below gives limits by country. These are typically blood alcohol content limits for the operation of a vehicle.

Zero effective tolerance

It is illegal to have any measurable alcohol in the blood while driving in these countries. Most jurisdictions have a tolerance slightly higher than zero to account for false positives and naturally occurring alcohol in the body. Some of the following jurisdictions have a general prohibition of alcohol.

0.02%
0.03%
0.04%
  • Lithuania (0.00% for car drivers in their first two years after gaining a driving license, motorcycle and truck drivers)
0.05%
  • Argentina (0.02% for motorbikes, 0.00% for truck, taxi, and bus drivers, 0.00% in the provinces of Cordoba and Salta)
  • Australia (0.00% for Australian Capital Territory learner, provisional and convicted DUI drivers (changed down from 0.02% on December 1, 2010), 0.02% for truck/bus/taxi, 0.00% for learner drivers, provisional/probationary drivers (regardless of age), truck and bus drivers, driving instructors and DUI drivers in all other states)
  • Austria – no limit for pedestrians; 0.08% for cycling; 0.05% generally for cars <7,5 t (driving licence B) and motorbikes (A); but 0,01% during learning (for driver and teacher or L17-assistant), during probation period (at least the first 2 years) or up to the age of 20 (A1, AM, L17, F), trucks (C >7,5 t), bus (D), drivers of taxi and public transport[23][24]
  • Belgium (also for cyclists)
  • Bulgaria
  • Canada: Alberta, British Columbia, Ontario, Manitoba, Newfoundland, Nova Scotia, New Brunswick—provincial offence. Drivers have not committed a criminal offense, however a 3-day licence suspension and 3-day vehicle seizure occurs.
  • Costa Rica[25]
  • Croatia—professional drivers, driving instructors and drivers of the vehicle categories C1, C1+E, C, C+E, D, D+E and H; the limit for other drivers is 0.50 mg/g, but they do get an additional separate fine if they cause an accident while having a blood alcohol level between 0 and 0,50 mg/g[26]
  • Denmark
  • Finland
  • France (0.025% for bus drivers)[27]
  • Germany (0.0% for learner drivers, all drivers 18–21 and newly licensed drivers of any age for first two years of licence; also, if the BAC exceeds 0.03%, driving is illegal if the driver is showing changes in behavior ("Relative Fahruntüchtigkeit"))
  • Greece
  • Hong Kong
  • Iceland
  • Ireland (0.02% for learner drivers and professional drivers)[28]
  • Israel 24 µg per 100 ml (0.024%) of breath (penalties only apply above 26 µg per 100 ml (0.026%) of breath due to lawsuits about sensitivity of devices used). This is equivalent to a BAC of 0.05. New drivers, drivers under 24 years of age and commercial drivers 5 µg per 100 ml of breath. This is equivalent to a BAC of 0.01.[14]
  • Italy (0.00% for drivers in their first three years after gaining a driving license)
  • Latvia (0.02% for drivers in their first two years after gaining a driving license)
  • Luxembourg
  • Macedonia (0.00% for drivers in their first two years after gaining a driving license)
  • Netherlands (0.02% for drivers in their first five years after gaining a driving license)[18]
  • New Zealand
  • Perù
  • Philippines (0.00% for taxicab and public transport drivers)[29]
  • Portugal (0.02% for drivers holding a driver's licence for less than three years, professional drivers, and drivers of taxis, heavy vehicles, emergency vehicles, public transport of children and carrying dangerous goods).
  • Scotland
  • Slovenia (0.00% for drivers in their first two years after gaining a drivers licence, drivers under 21 and professional drivers, such as buses, trucks...)
  • South Africa
  • Spain (0.03% for drivers in their first two years after gaining a driving license and common carriers, such as buses, trucks...)
  • Switzerland (0.01% for drivers in their first three years after gaining a drivers licence and for driving instructors)[30]
  • Thailand
  • Taiwan (breath alcohol limit decreased from 0.25 to 0.15 from 13 June 2013)
  • Turkey
0.06%
0.07%
0.08%
0.1%

Limits by country (BrAC: breath alcohol content)

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In certain countries, alcohol limits are determined by the breath alcohol content (BrAC), not to be confused with blood alcohol content (BAC).

  • In Greece, the BrAC limit is 250 microgrammes of alcohol per litre of breath. The limit in blood is 0.50 g/l. The BrAC limit for drivers in their first two years after gaining a driving license and common carriers are more restricted to 100 microgrammes per litre of breath.
    • BrAC 250–400 = 200 fine.
    • BrAC 400–600 = €700 fine, plus suspension of driving license for 90 days (introduced in 2007)[40]
    • BrAC >600 = 2 months imprisonment, plus suspension of driving license for 180 days, plus €1,200 fine
  • In Hong Kong, the BrAC limit is 220 microgrammes per litre of breath (as well as other defined limits)
  • In The Netherlands and Finland, the BrAC limit is 220 microgrammes of alcohol per litre of breath (μg/l, colloquially known as "Ugl").
  • In New Zealand, the BrAC limit is 250 microgrammes of alcohol per litre of breath for those aged 20 years or over, and zero (meaning illegal to have any measurable breath alcohol content) for those aged under 20 years.[41]
  • In Singapore, the BrAC limit is 350 microgrammes of alcohol per litre of breath.[36]
  • In Spain the BrAC limit is 250 microgrammes of alcohol per litre of breath and 150 microgrammes per litre of breath for drivers in their first two years after gaining a driving license and common carriers.
  • In England and Wales the BrAC limit is 350 microgrammes of alcohol per litre of breath (as well as the above defined blood alcohol content).
  • In Scotland the BrAC limit is 220 microgrammes of alcohol per litre of breath (as well as the above defined blood alcohol content).
  • In Trinidad and Tobago the BrAC limit is 35 microgrammes of alcohol per 100 millilitres of breath (as well as the above defined blood alcohol content).

Other limitation schemes

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  • For South Korea, the penalties for different blood alcohol content levels include
    • 0.01–0.049 = No penalty
    • 0.05–0.09 = 100 days license suspension
    • >0.10 = Cancellation of car license.

Test assumptions

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Template:Refimprove Blood alcohol tests assume the individual being tested is average in various ways. For example, on average the ratio of blood alcohol content to breath alcohol content (the partition ratio) is 2100 to 1. In other words, there are 2100 parts of alcohol in the blood for every part in the breath. However, the actual ratio in any given individual can vary from 1300:1 to 3100:1, or even more widely.[42][43] This ratio varies not only from person to person, but within one person from moment to moment. Thus a person with a true blood alcohol level of .08% but a partition ratio of 1700:1 at the time of testing would have a .10 reading on a Breathalyzer calibrated for the average 2100:1 ratio.

A similar assumption is made in urinalysis. When urine is analyzed for alcohol, the assumption is that there are 1.3 parts of alcohol in the urine for every 1 part in the blood, even though the actual ratio can vary greatly.

Breath alcohol testing further assumes that the test is post-absorptive—that is, that the absorption of alcohol in the subject's body is complete.[44] If the subject is still actively absorbing alcohol, their body has not reached a state of equilibrium where the concentration of alcohol is uniform throughout the body. Most forensic alcohol experts reject test results during this period as the amounts of alcohol in the breath will not accurately reflect a true concentration in the blood.

Metabolism and excretion

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Template:Refimprove Alcohol is absorbed throughout the gastrointestinal tract, but more slowly in the stomach than in the small or large intestine. For this reason, alcohol consumed with food is absorbed more slowly, because it spends a longer time in the stomach. Furthermore, alcohol dehydrogenase is present in the stomach lining. After absorption, the alcohol passes to the liver through the hepatic portal vein, where it undergoes a first pass of metabolism before entering the general bloodstream.[45]

Alcohol is removed from the bloodstream by a combination of metabolism, excretion, and evaporation. The relative proportion disposed of in each way varies from person to person, but typically about 95% is metabolized by the liver. The remainder of the alcohol is eliminated through excretion in breath, urine, sweat, feces, milk and saliva.[46] Excretion into urine typically begins after about 40 minutes, whereas metabolisation commences as soon as the alcohol is absorbed, and even before alcohol levels have risen in the brain.

Alcohol is metabolized mainly by the group of six enzymes collectively called alcohol dehydrogenase. These convert the ethanol into acetaldehyde (an intermediate more toxic than ethanol). The enzyme acetaldehyde dehydrogenase then converts the acetaldehyde into non-toxic acetic acid.

Many physiologically active materials are removed from the bloodstream (whether by metabolism or excretion) at a rate proportional to the current concentration, so that they exhibit exponential decay with a characteristic halflife (see pharmacokinetics). This is not true for alcohol, however. Typical doses of alcohol actually saturate the enzymes' capacity, so that alcohol is removed from the bloodstream at an approximately constant rate. This rate varies considerably between individuals. Another sex based difference is in the elimination of alcohol. People under 25[senza fonte], women[47] or with liver disease may process alcohol more slowly. False High (BAC) readings are related to patients with proteinuria and hematuria, due to kidney-liver metabolism and failure (for example, Hematuria 1+ protenuria 1+ )

Such persons have impaired acetaldehyde dehydrogenase, which causes acetaldehyde levels to peak higher, producing more severe hangovers and other effects such as flushing and tachycardia. Conversely, members of certain ethnicities that traditionally did not use alcoholic beverages have lower levels of alcohol dehydrogenases and thus "sober up" very slowly, but reach lower aldehyde concentrations and have milder hangovers. Rate of detoxification of alcohol can also be slowed by certain drugs which interfere with the action of alcohol dehydrogenases, notably aspirin, furfural (which may be found in fusel alcohol), fumes of certain solvents, many heavy metals, and some pyrazole compounds. Also suspected of having this effect are cimetidine (Tagamet), ranitidine (Zantac), and acetaminophen (Tylenol) (paracetamol).

Currently, the only known substance that can increase the rate of metabolism of alcohol is fructose. The effect can vary significantly from person to person, but a 100 g dose of fructose has been shown to increase alcohol metabolism by an average of 80%. Fructose also increases false positives of high BAC ratio readings in anyone with proteinuria and hematuria, due to kidney-liver metabolism.[48]

Full stomachs

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Alcohol absorption can be slowed by ingesting alcohol on a full stomach.[49] Spreading the total absorption of alcohol over a greater period of time decreases the maximum alcohol level, decreasing the hangover effect. Thus, drinking on a full stomach or drinking while ingesting drugs which slow the breakdown of ethanol into acetaldehyde will reduce the maximum blood levels of this substance and thus decrease the hangover. [senza fonte]

Carbonated beverages

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Lo stesso argomento in dettaglio: Carbonated water § Metabolism and excretion.

Alcohol in carbonated beverages is absorbed faster than alcohol in non-carbonated drinks.[49][50] Another study also confirmed this, conducted at the University of Surrey in the United Kingdom gave subjects equal amounts of flat and sparkling champagne which contained the same levels of alcohol. After 5 minutes following consumption, the group that had the sparkling wine had 54 milligrams of alcohol in their blood while the group that had the same wine, only flat, had 39 milligrams.[4]

Being under stress causes alcohol to metabolize faster.[49][51][52]

Retrograde extrapolation

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Retrograde extrapolation is the mathematical process by which someone's blood alcohol concentration at the time of driving is estimated by projecting backwards from a later chemical test. This involves estimating the absorption and elimination of alcohol in the interim between driving and testing. The rate of elimination in the average person is commonly estimated at .015 to .020 grams per deciliter per hour (g/dl/h),[53] although again this can vary from person to person and in a given person from one moment to another. Metabolism can be affected by numerous factors, including such things as body temperature, the type of alcoholic beverage consumed, and the amount and type of food consumed.

In an increasing number of states, laws have been enacted to facilitate this speculative task: the blood alcohol content at the time of driving is legally presumed to be the same as when later tested. There are usually time limits put on this presumption, commonly two or three hours, and the defendant is permitted to offer evidence to rebut this presumption.

Forward extrapolation can also be attempted. If the amount of alcohol consumed is known, along with such variables as the weight and sex of the subject and period and rate of consumption, the blood alcohol level can be estimated by extrapolating forward. Although subject to the same infirmities as retrograde extrapolation—guessing based upon averages and unknown variables—this can be relevant in estimating BAC when driving and/or corroborating or contradicting the results of a later chemical test.

Highest recorded blood alcohol level/content

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There have been reported cases of blood alcohol content higher than 1%:

  • On 26 October 2012 a man from Gmina Olszewo-Borki, Poland, who died in a car accident, recorded a blood alcohol content of 2.23%; however, the blood sample was collected from a wound and thus possibly contaminated.[54]
  • In South Africa, a man driving a Mercedes-Benz Vito light van containing 15 sheep, allegedly stolen from nearby farms, was arrested on December 22, 2010, near Queenstown in Eastern Cape. His blood had an alcohol content of 1.6%. Also in the vehicle were five boys and a woman who were also arrested.[55]
  • In 1982, a 24-year-old woman was admitted to the UCLA emergency room with a serum alcohol content of 1.51%, corresponding to a BAC of 1.33%. She was alert and oriented to person and place.[56] Serum alcohol concentration is not equal to nor calculated in the same way as blood alcohol content.[57]
  • In 1984 a 30-year-old man survived a blood alcohol concentration of 1.5% after vigorous medical intervention that included dialysis and intravenous therapy with fructose.[58]
  • In 1995, a man from Wrocław caused a car accident near his hometown. He had a blood alcohol content of 1.48% ; he was tested five times but all results were the same. He died a few days later of injuries from the accident.[59]
  • In 2013, on July 26 a 40-year-old man from Alfredówka, Poland, was found by Municipal Police Patrol from Nowa Dęba lying in the ditch along the road in Tarnowska Wola. At the hospital there was recorded that the man had a blood alcohol content of 1.374%. The man survived.[60][61]
  • In 2004, an unidentified Taiwanese woman died of alcohol intoxication after immersion for twelve hours in a bathtub filled with 40% ethanol. Her blood alcohol content was 1.35%. It was believed that she had immersed herself as a response to the SARS epidemic.[62]
  • In March 2009, a 45-year-old man was admitted to the hospital in Skierniewice, Poland, after being struck by a car. The blood test showed blood alcohol content at 1.23%. The man survived but did not remember either the accident or the circumstances of his alcohol consumption.[63]
  • In Poland, a homeless man was found sleeping half-naked on January 28, 2011, in Cieszyn. His blood had an alcohol level of 1.024%. Despite the temperature of −10 °C and extremely high blood alcohol content, the man survived.[64]
  • In February 2005, French gendarmes from Bourg-en-Bresse, France, conducted a breath test on a man who had lost control of his car. He had an alcohol content of 0.976%.[65] He was not injured in the accident but received a custodial sentence and his driving license was canceled.
  • In December 2004, a man was admitted to the hospital in Plovdiv, Bulgaria, after being struck by a car. After detecting a strong alcohol odor, doctors at a hospital conducted a breath test which displayed the man's blood alcohol content at 0.914%.[66] The man was treated for serious injuries sustained in the crash and survived.[67]
  1. ^ A hybridizing of effects as described at Alcohol's Effects Archiviato il May 5, 2007 Data nell'URL non combaciante: 5 maggio 2007 in Internet Archive. from Virginia Tech and Federal Aviation Regulation (CFR) 91.17: Alcohol and Flying (hosted on FlightPhysical.com)
  2. ^ a b Alcohol use among university students in Sweden measured by an electronic screening instrument, in BMC Public Health, vol. 9, 2009, p. 229, DOI:10.1186/1471-2458-9-229.
  3. ^ Determination of volume of distribution for ethanol in male and female subjects, in Journal of analytical toxicology, vol. 20, n. 5, 1996, pp. 287–90, DOI:10.1093/jat/20.5.287.
  4. ^ a b G. Harding "A Wine Miscellany" pg 136–137, Clarkson Potter Publishing, New York 2005 ISBN 0-307-34635-8
  5. ^ Based on the CDC standard of 0.6 fl oz alcohol per drink. CDC alcohol FAQ
  6. ^ BAC Charts Archiviato il June 30, 2007 Data nell'URL non combaciante: 30 giugno 2007 in Internet Archive. from Virginia Tech
  7. ^ "Quick Stats: Binge Drinking." The Centers for Disease Control and Prevention. April 2008.[1].
  8. ^ Research Blood Alcohol Concentration – Drugs, Alcohol, and Tobacco, in www.BookRags.com.
  9. ^ The Various Alcohol and Drug Related Prohibitions and Suspensions – Prohibitions and Suspensions – RoadSafetyBC, su pssg.gov.bc.ca.
  10. ^ Newsroom : Keeping Drivers Safe, in news.ontario.ca.
  11. ^ Tolérance zéro pour les conducteurs de moins de 21 ans, in La Presse.
  12. ^ Tolerancia cero: ni una cerveza si va a conducir, in eltiempo.com.
  13. ^ http://wsp.presidencia.gov.co/Normativa/Leyes/Documents/2013/LEY%201696%20DEL%2019%20DE%20DICIEMBRE%20DE%202013.pdf
  14. ^ a b Alcohol and Driving, su he.mot.gov.il, Ministry of Transport. URL consultato il 2 July 2012.
  15. ^ Medvedev signs total drink driving ban, su en.rian.ru, RIAN, 23 luglio 2010.
  16. ^ a b Russian drivers to be allowed to have slight alcohol content in blood, su itar-tass.com, Itar-tass, 26 luglio 2013.
  17. ^ Alcohol cero rige a partir de 2016, su elpais.com.uy.
  18. ^ a b Alcohol, su alcohollimiet.nl.
  19. ^ /d: LOV-1965-06-18-4 :d/ Lov om vegtrafikk (vegtrafikkloven)
  20. ^ a b [2]
  21. ^ according to Section 185 of Motor Vehicles Act 1988. On first offence, the punishment is imprisonment of 6 months and/or fine of 2000 Indian Rupees (INR). If the second offence is committed within three years, the punishment is 2 years and/or fine of 3000 Indian Rupees (INR). The clause of 30 mg/dL was added by an amendment in 1994. It came into effect beginning 14 November 1994.
  22. ^ http://www.npa.go.jp/annai/license_renewal/english.pdf The breath alcohol concentration limit for driving in Japan is 0.15 mg/l, which, assuming a breath alcohol to blood alcohol ratio of 1:2,100, is roughly equivalent to a BAC of 0.0315%. The penalties become even more severe at 0.25 mg/l, which is roughly equivalent to a BAC of 0.0525%.
  23. ^ https://www.help.gv.at/Portal.Node/hlpd/public/content/4/Seite.042000.html Alkohol am Steuer, HELP.gv.at, of 19. January 2013, retr. 22. April 2013
  24. ^ http://www.verkehrspsychologie.at/gesetzliche_grundlagen_fuehrerscheinentzug.htm Gesetzliche Grundlagen für den Führerscheinentzug (Alkohol), verkehrspsychologie.at, AAP – Angewandte Psychologie und Forschung GmbH, Wien, retr. 22. April 2013
  25. ^ Chart, su driveandstayalive.com. URL consultato il 20 luglio 2015.
  26. ^ Driving law (hr)
  27. ^ Between 0.05% and 0.08%, drivers can be fined €135 and have six points removed from their licence. Above 0.08%, the punishment is more severe with possible imprisonment of up to two years, heavy fines and licence suspension. Archived copy, su www2.securiteroutiere.gouv.fr. URL consultato il 23 giugno 2008 (archiviato dall'url originale il 1º dicembre 2008). (in French)
  28. ^ [3]
  29. ^ BAC and BrAC Limits – International Alliance for Responsible Drinking, in International Alliance for Responsible Drinking.
  30. ^ Quoi de neuf en 2014 ?, su tcs.ch.
  31. ^ Driving Under the Influence Unit, su royalbahamaspolice.org.
  32. ^ Drinking and Driving: SAAQ
  33. ^ The drink drive limit, su direct.gov.uk.
  34. ^ /d: LOV-1998-06-26-47 :d/ Lov om fritids- og småbåter
  35. ^ DOE – Biggest shake up in drink driving laws for forty years – Attwood
  36. ^ a b Driving In Singapore – Home Archiviato il February 2, 2008 Data nell'URL non combaciante: 2 febbraio 2008 in Internet Archive.
  37. ^ National Institute of Alcohol Abuse and Alcoholism. http://alcoholpolicy.niaaa.nih.gov/Blood_Alcohol_Concentration_Limits_Adult_Operators_of_Noncommercial_Motor_Vehicles.html. Accessed on February 01, 2013.
  38. ^ Commercial Driver's License Program, in Federal Motor Carrier Safety Administration.
  39. ^ 18 U.S.C. § 343  : US Code – Section 343: Presumptions, in Findlaw.
  40. ^ Archived copy (PDF), su sefeaa.gr. URL consultato il 28 novembre 2009 (archiviato dall'url originale il 7 ottobre 2009).
  41. ^ Alcohol and drug limits, in Driving Tests Resources.
  42. ^ Archived copy, su denverdui.com. URL consultato il 4 dicembre 2012 (archiviato dall'url originale il 24 giugno 2012).
  43. ^ Alobaidi TA, Hill DW, Payne JP, Significance of variations in blood: breath partition coefficient of alcohol., in Br Med J, vol. 2, 1976, pp. 1479–81, DOI:10.1136/bmj.2.6050.1479.
  44. ^ Archived copy, su duiblog.com. URL consultato il 4 dicembre 2012 (archiviato dall'url originale il 12 gennaio 2013).Template:Full citation neededTemplate:Self-published inline
  45. ^ Alan J.Buglass (a cura di), Handbook of alcoholic beverages : technical, analytical and nutritional aspects, Chichester, Wiley, 2011, ISBN 978-0-470-97665-4. URL consultato il 6 July 2013.
  46. ^ Alcohol and the Human Body
  47. ^ Gender Differences in Alcohol Metabolism, in Recent Developments in Alcoholism, 2002, pp. 163–72, DOI:10.1007/0-306-47138-8_9, ISBN 0-306-44921-8.
  48. ^ Fructose & ethanol
  49. ^ a b c Absorption Rate Factors, su bhs.umn.edu.
    «When food is ingested, the pyloric valve at the bottom of the stomach will close in order to hold food in the stomach for digestion and thus keep the alcohol from reaching the small intestine. The larger the meal and closer in time to drinking, the lower the peak of alcohol concentration; some studies indicate up to a 20% reduction in peak blood alcohol level.
    Stress causes the stomach to empty directly into the small intestine, where alcohol is absorbed even faster.
    Liquor mixed with soda or other bubbly drinks speeds up the passage of alcohol from the stomach to the small intestine, which increases the speed of absorption.»
  50. ^ Alcohol concentration and carbonation of drinks: The effect on blood alcohol levels, in Journal of Forensic and Legal Medicine, vol. 14, n. 7, 2007, pp. 398–405, DOI:10.1016/j.jflm.2006.12.010.
  51. ^ Holt S, Observations on the relation between alcohol absorption and the rate of gastric emptying, in Can Med Assoc J, vol. 124, 1º February 1981, pp. 267–77, 297.
  52. ^ LEIKOLA A, Influence of stress on alcohol intoxication in rats., in Q J Stud Alcohol, vol. 23, pp. 369–75.
  53. ^ Retrograde extrapolation of blood alcohol data: An applied approach, in Journal of Toxicology and Environmental Health, vol. 36, n. 4, 1992, pp. 281–92, DOI:10.1080/15287399209531639.
  54. ^ [http://www.eostroleka.pl/smiertelny-rekord-kierowca-z-powiatu-ostroleckiego-mial-22-promile-alkoholu-zginal-w-wypadku-zdjecia,art31892.html%5B%5D Strona nie zosta�a znaleziona - B��d 404], su eostroleka.pl.
  55. ^ Drunkest driver in SA arrested Sowetan
  56. ^ Survival After a Serum Ethanol Concentration of 11/2%, in The Lancet, vol. 320, n. 8312, 1982, p. 1394, DOI:10.1016/S0140-6736(82)91285-5.
  57. ^ Conversion of Serum-Alcohol Concentrations to Corresponding Blood-Alcohol Concentrations, in Journal of Chemical Education, vol. 79, n. 7, 2002, p. 803, DOI:10.1021/ed079p803.
  58. ^ Survival After High Blood Alcohol Levels: Association with First-Order Elimination Kinetics, in Archives of Internal Medicine, vol. 144, n. 3, 1984, pp. 641–2, DOI:10.1001/archinte.1984.00350150255052.
  59. ^ Śmiertelny rekord: Kierowca z powiatu ostrołęckiego miał 22 promile alkoholu! Zginął w wypadku [ZDJĘCIA], in eOstroleka.pl – Twoje Wirtualne Miasto, 24 October 2012.
  60. ^ Archived copy, su wiadomosci.gazeta.pl. URL consultato l'8 agosto 2013 (archiviato dall'url originale l'11 agosto 2013).
  61. ^ Informacje, su nowadeba.pl.
  62. ^ Fatal alcohol immersion during the SARS epidemic in Taiwan, in Forensic Science International, vol. 149, 2–3, 2005, p. 287, DOI:10.1016/j.forsciint.2004.06.014.
  63. ^ The Drunkest Drinking Driver in Sweden: Blood Alcohol Concentration 0.545% w/v, in Journal of Studies on Alcohol and Drugs, vol. 60, n. 3, 1999, pp. 400–6.[collegamento interrotto]
  64. ^ [4] Sowetan
  65. ^ Alcool : 10 g au volant, le record de contrôle absolu ! - Société – MYTF1News, in MYTF1NEWS, 4 February 2005.
  66. ^ Bulgarian's blood-alcohol level astounds doctors, CBC News, January 4, 2005 (retrieved on March 16, 2009).
  67. ^ Bulgarian Sets World Record for Highest Blood Alcohol Level, Sofia News Agency (Novinte.com), January 4, 2005 (retrieved on March 31, 2009).
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